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A biotinylated reagent used for the detection and quantification of apurinic/apyrimidinic (AP) sites in damaged DNA; reacts with aldehyde groups formed when reactive oxygen species depurinate DNA, thereby covalently linking biotin to these AP sites.
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The family of aldehyde dehydrogenase (ALDH)nbspcontainsnbsp19 genes in humans. It isnbsplocalized innbspthenbspnucleus cytosol mitochondria and endoplasmic reticulum of thenbspcell.
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m-PEG3-aldehyde (stabilized with BHT) is a polyethylene glycol-based aldehyde linker used as a building block in the chemical synthesis of PROTACs and other bioconjugates. It provides a short PEG spacer with a reactive aldehyde terminus suitable for conjugation to hydrazide, aminooxy, or amine-functional groups.
Provides an aldehyde-terminated PEG3 spacer for conjugation.
Molecular formula C8H16O4 and molecular weight 176.21.
High purity (98.0%).
Appearance liquid, colorless to light yellow.
CAS number 356066-46-1.
Available in small milligram pack sizes for research use.
Recommended long-term storage at -20°C under nitrogen; in solvent: -80°C for 6 months, -20°C for 1 month.
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